Mitochondrial Disorders

Mitochondrial disorders or diseases, are a group of rare and complex disorders caused by mutations in the mitochondrial DNA (mtDNA) or nuclear DNA that affect the function of mitochondria. Some examples are:

• Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)
• Leigh syndrome
• Myoclonic epilepsy with ragged red fibers (MERRF)
• Chronic Progressive External Ophthalmoplegia (CPEO)
• Mitochondrial DNA depletion syndromes
• Mitochondrial Neurogastrointestinal Encephalopathy (MNGIE)
• Leber’s Hereditary Optic Neuropathy (LHON)
• Mitochondrial myopathy
• Mitochondrial cardiomyopathy
• Sensorineural hearing loss associated with mitochondrial disorders
• Mitochondrial ataxias
• Mitochondrial diabetes